3-Hydroxyflavone, 98+%

Description

CAS: 577-85-5 | C15H10O3 | 238.24 g/mol

3-Hydroxyflavone is a reactant involved in studies of photochemically-induced dioxygenase-type CO-release reactivity; phase-transfer protection and deprotection of hydroxychromones; and O-methylation with di-Me carbonate. As a reactant it is involved in the synthesis of biologically active molecules including 2-chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors; dihydrochromenopyrazines and chromenoquinoxalines. It is also involved in studies of its electrochemical properties using voltammetric methodologies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Hydroxyflavone is a reactant involved in studies of photochemically-induced dioxygenase-type CO-release reactivity; phase-transfer protection and deprotection of hydroxychromones; and O-methylation with di-Me carbonate. As a reactant it is involved in the synthesis of biologically active molecules including 2-chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors; dihydrochromenopyrazines and chromenoquinoxalines. It is also involved in studies of its electrochemical properties using voltammetric methodologies.

Solubility
Insoluble in water. Soluble in N,N-DMF and ethanol.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 577-85-5
• Molecular Formula: C15H10O3
• Molecular Weight (g/mol): 238.24
• MDL Number: MFCD00006832
• InChI Key: HVQAJTFOCKOKIN-UHFFFAOYSA-N
• Synonym: 3-hydroxyflavone, flavonol, 3-hydroxy-2-phenyl-4h-chromen-4-one, flavon-3-ol, 4h-1-benzopyran-4-one, 3-hydroxy-2-phenyl, flavone, 3-hydroxy, 3-hydroxy-2-phenylchromone, unii-ztg9lss5qh, flavone,3-hydroxy, 3-hf
• PubChem CID: 11349
• ChEBI: CHEBI:5078
• IUPAC Name: 3-hydroxy-2-phenylchromen-4-one
• SMILES: OC1=C(OC2=CC=CC=C2C1=O)C1=CC=CC=C1

• Melting Point: 168°C to 172°C
• Quantity: 5 g
• Beilstein: 15789
• Solubility Information: Insoluble in water. Soluble in N,N-DMF and ethanol.
• Formula Weight: 238.25
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Hydroxyflavone

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement P261-P280-P305+P351+P338-P304+P340-P405-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	209-416-9
RTECSNumber	LK8650000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only