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Medchemexpress LLC 3-Isoquinolinamine, N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidinyl]-4-pyrimidinyl]-5-(1-met | 2660250-10-0 | 99.4% | C28H37FN6O3S | 50 MG

Supplier: Medchemexpress LLC HY14468050MG
BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation. This product is used for the research of lung cancer, including non-small cell lung cancer (NSCLC).
- Potent and highly selective EGFR tyrosine kinase inhibitor
- Reversible and orally active
- Inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation
- Used for research of lung cancer, including non-small cell lung cancer
- Shows inhibitory activity against EGFRm/T790M double and EGFRm/T790M/C797S triple mutants
- Demonstrates robust EGFR pathway inhibition and anti-tumor activity in triple-mutant Osimertinib-resistant models
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