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Cayman Chemical 3-keto UrsolIc AcId 250mg

Supplier: Cayman Chemical 37364250 MG

A calcium channel inhibitor selective for the voltage-gated calcium channels Cav2.2 and Cav2.1 over Cav1.2 at 30 UM inhibits increases in intracellular calcium levels induced by NMDA L-glutamic acid or veratridine in primary rat cerebellar granule cells at 10 UM reduces glutamate but not aspartate release from the left caudate nucleus in cats at 10 UM reduces slow wave activity and increases high frequency neuronal activity induced by CAO in gerbils in a dose-dependent manner and decreases the CAO-induced infarcted cortex volume in rats at 8 mg/kg increases survival time and total distance ran in an SOD1-G93A transgenic mouse model of ALS at 44 mg/kg per day in the diet
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