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Enzo Life Sciences 3-Morpholinosydnonimine (100mg). CAS: 33876-97-0
Supplier: Enzo Life Sciences BMLCN2450100
SIN-1 is a metabolite of molsidomine which decomposes spontaneously in solution in the presence of oxygen, releasing NO and superoxide anion under physiological conditions. Since NO and superoxide react to form peroxynitrite, SIN-1 may actually produce peroxynitrite under physiological conditions. It is a potent vasodilator and inhibitor of platelet aggregation and produces significant protective effects in myocardial ischemia-reperfusion. The effects of SIN-1 are markedly attenuated by nitroglycerin-induced tolerance. Inhibits cysteine proteases. Alternative name: SIN-1, Linsidomine. Purity: ≥98% (HPLC). Solubility: Soluble in water (25mg/ml), 100% ethanol or DMSO (>5mg/ml). Long Term Storage: -20°C.
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