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Medchemexpress LLC 3-Nitrocoumarin | 28448-04-6 | 100.0% | 191.14 | 1 ML

Supplier: Medchemexpress LLC HY11191910MM/1ML
3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway. This compound causes morphological changes of apical hyperbranching in *N. crassa* hyphae.
- Inhibits phospholipase C, affecting the calcium signaling pathway.
- Inhibits glucose-induced increase of intracellular calcium ions in yeast strain WPY260 (at 50 mg/mL for 6 min).
- Inhibits PLC in *Neurospora crassa* with an IC50 of 10 μg/mL.
- Inhibits the growth of *N. crassa* and causes morphological changes of apical hyperbranching in hyphae.
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