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3-Nitrophthalic anhydride, 97%
Description
4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.
Solubility
May decompose in water.
Notes
Air sensitive. Store at room temperature. Keep away from oxidizing agents.

Specifications
Specifications
Melting Point | 161°C to 166°C |
Quantity | 100 g |
Beilstein | 179963 |
Sensitivity | Moisture sensitive |
Solubility Information | May decompose in water. |
IUPAC Name | 4-nitro-2-benzofuran-1,3-dione |
Formula Weight | 193.11 |
Percent Purity | 97% |
Chemical Name or Material | 3-Nitrophthalic anhydride |
Safety and Handling
Hazard Category | H315-H319-H335 |
Hazard Statement | GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
Precautionary Statement | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c |
EINECSNumber | 211-373-6 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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