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Apexbio Technology LLC N-3-oxo-dodecanoyl-L-Homoserine lactone(Synonyms: 3-Oxo-C12-HSL, N-(3-Oxododecanoyl)-L-homoserine lactone, OdDHL, 3-Oxododecanoyl homoserine lactone), 10mg, CAS: 168982-69-2.
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Supplier:  Apexbio Technology LLC C410710

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N-3-oxo-dodecanoyl-L-Homoserine lactone (CAS 168982-69-2) commonly termed 3-O-C12-HSL is an acylhomoserine lactone (AHL) molecule utilized by Gram-negative bacteria such as Pseudomonas aeruginosa for quorum sensing This small lipid-soluble signaling molecule modulates virulence gene expression in response to bacterial population density In human pulmonary epithelial (16HBE) and lung fibroblast (L828) cell models exposure to 3-O-C12-HSL strongly elevates IL-8 transcription and secretion subsequently promoting neutrophil chemotaxis Thus 3-O-C12-HSL is extensively studied in pathogen-host interactions notably in respiratory infections associated with cystic fibrosis

Catalog No. 50-000-61326


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