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Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY18053

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AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM. It is for research use only.

  • Potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 7 nM.
  • Displays excellent selectivity versus related enzymes such as 11-βHSD2, 17β-HSD1, 17β-HSD3 (all IC50 > 30 μM).
  • Shows no measurable activity against glucocorticoid and mineralocorticoid receptors.
  • Potent inhibitor of 11β-HSD1 activity in isolated human adipocytes from nondiabetic volunteers, with an IC50 of 0.002 μM.
  • Appearance: solid.
  • Color: light yellow to yellow.

Catalog No. 50-003-84103


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