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Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 25MG
SDP

Supplier:  Medchemexpress LLC HY12461925MG

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GPI-1046 is an orally active, non-immunosuppressive immunophilin ligand with reported neuroprotective properties. It has been shown to reduce ethanol intake by upregulating the glutamate transporter GLT1 and to improve HIV-associated sensory neuropathy by attenuating store-operated calcium (SOC) entry. The compound is provided as a high-purity research chemical in solid and ready-to-use DMSO formulations for preclinical pharmacology studies.

  • Has neuroprotective activity demonstrated in preclinical studies.
  • Upregulates the glutamate transporter GLT1 in relevant brain regions.
  • Attenuates store-operated calcium entry implicated in neuropathy.
  • Provided at high reported purity for research applications.
  • Available as solid packs and DMSO solutions for dosing flexibility.

Catalog No. 50-002-36178


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