Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000439893

Medchemexpress LLC 3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl]-β-(2-fluoro-3-methoxyphenyl)-2-methoxy- | 2252316-16-6 | 99.7% | 614.50 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY111747

Encompass_Preferred

TBAJ-587 is a potent anti-tuberculosis agent, an analogue of Bedaquiline, demonstrating more potent anti-tubercular activity. It inhibits *M.tb* strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assays, respectively. A key feature of TBAJ-587 is its greatly attenuated inhibition of the cardiac potassium channel protein hERG compared to Bedaquiline, with an IC50 of 13 μM for hERG channel inhibition, thus reducing cardiac liability.

  • Potent anti-tuberculosis agent.
  • Inhibits *M.tb* strain H37Rv growth.
  • Minimally inhibits the hERG channel.
  • Reduces cardiac liability compared to Bedaquiline.

Catalog No. 50-004-39893


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.