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Medchemexpress LLC 3-Thiophenecarboxylic acid, 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methyl-, methyl ester | 544450-68-2 | 99.94% | 337.82 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY137204100MG

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COR659 is a potent and effective GABAB positive allosteric modulator (PAM) that suppresses alcohol and chocolate self-administration in rats. Its effects are exerted through a composite mechanism, involving positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor.

  • Potent and effective GABAB positive allosteric modulator (PAM).
  • Suppresses alcohol and chocolate self-administration in rats.
  • Exerts effects through a composite mechanism.
  • Involves positive allosteric modulation of the GABAB receptor.
  • Acts at the cannabinoid CB1 receptor.
  • Has shown cytotoxicity against mouse NIH/3T3 cells with an IC50 of 59 μM.
  • Relevant to research in neurological, eye or ear disease, neurodegenerative disease, depression, Alzheimer's disease, and Parkinson's disease.

Catalog No. 50-003-51298


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