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3-(Trimethylsilyl)propargyl alcohol, 98%
Description
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
Solubility
Not miscible with water.
Notes
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.

Specifications
Specifications
Boiling Point | 170°C to 172°C |
Quantity | 25 g |
Linear Formula | (CH3)3SiC≡CCH2OH |
UN Number | UN2810 |
Beilstein | 1902505 |
Flash Point | 66°C (150°F) |
Solubility Information | Not miscible with water. |
Formula Weight | 128.25 |
Percent Purity | ≥98% |
Refractive Index | 1.451 |
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Safety and Handling
Hazard Category | H227-H315-H319-H335 |
Hazard Statement | GHS H Statement H301-H227-H315-H319-H335 Toxic if swallowed. Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
Precautionary Statement | P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c |
DOTInformation | Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S. |
EINECSNumber | 226-094-5 |
TSCA | Yes |
Recommended Storage | Keep cold |
RUO – Research Use Only
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