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Medchemexpress LLC 306-N16B | 2803699-70-7 | C75H151N7O4S8 | 5 MG
SDP

Catalog No. 5000375313
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306-N16B is a selective lung-targeted lipid nanoparticle designed for efficient gene delivery to specific cells within the lungs. It achieves this by reversibly targeting lung endothelial cells and immune cells through the formation of a protein corona in the bloodstream. This protein corona, influenced by the nanoparticle's tail structure, guides the particles to accumulate in the lungs, facilitating the release of mRNA and promoting target cell gene expression.

  • Selectively targets lung endothelial and immune cells.
  • Utilizes a protein corona for lung-specific enrichment.
  • Promotes efficient mRNA release and gene expression.
  • Enables precise regulation of gene delivery to various lung cell types.
  • Potential for gene therapy in hereditary lung diseases (e.g., LAM).
  • Applicable in lung-specific mRNA vaccines and gene editing.

Catalog No. 50-003-75313 Supplier Medchemexpress LLC Supplier No. HY1502295MG
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306-N16B is a selective lung-targeted lipid nanoparticle designed for efficient gene delivery to specific cells within the lungs. It achieves this by reversibly targeting lung endothelial cells and immune cells through the formation of a protein corona in the bloodstream. This protein corona, influenced by the nanoparticle's tail structure, guides the particles to accumulate in the lungs, facilitating the release of mRNA and promoting target cell gene expression.

  • Selectively targets lung endothelial and immune cells.
  • Utilizes a protein corona for lung-specific enrichment.
  • Promotes efficient mRNA release and gene expression.
  • Enables precise regulation of gene delivery to various lung cell types.
  • Potential for gene therapy in hereditary lung diseases (e.g., LAM).
  • Applicable in lung-specific mRNA vaccines and gene editing.

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