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ILEX LIFE SCIENCES LLC Cellendes 3-D Life ToGro Hydrogel Ready-To-Go Kit (1 Kit)
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Catalog No. NC2081813
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3-D Life is the most flexible system for biomimetic hydrogel design for 3D cell cultures. It uses two polymers that form a hydrogel by covalent crosslinking at ambient temperature. The chemical reaction is non-toxic to cells and occurs rapidly, preventing cell settlement before gel is formed. The 3-D Life ToGro Ready-To-Go Hydrogel Kit allows preparation of hydrogels with soft stiffness (400 Pa; shear modulus) and 0.4 mmol/L RGD Peptide concentration. This gel allows 3D spreading and migration of most cells. The gel is formed by crosslinking of RGD-Dextran with CD-Link. Thiol groups on CD-Link form stable thioether bonds with thiol-reactive groups on RGD-Dextran resulting in gel formation within 20 min. CD-Link is designed for MMP cleavage, allowing cell spreading/migration if they express the indicated MMPs. ToGro hydrogels can be dissolved by adding dextranase, allowing easy cell recovery. One kit allows formation of 2.4 ml ToGro Hydrogel. Manufactured in Germany by Cellendes GmbH.

Catalog No. NC2081813 Supplier ILEX LIFE SCIENCES LLC Supplier No. G941
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3-D Life is the most flexible system for biomimetic hydrogel design for 3D cell cultures. It uses two polymers that form a hydrogel by covalent crosslinking at ambient temperature. The chemical reaction is non-toxic to cells and occurs rapidly, preventing cell settlement before gel is formed. The 3-D Life ToGro Ready-To-Go Hydrogel Kit allows preparation of hydrogels with soft stiffness (400 Pa; shear modulus) and 0.4 mmol/L RGD Peptide concentration. This gel allows 3D spreading and migration of most cells. The gel is formed by crosslinking of RGD-Dextran with CD-Link. Thiol groups on CD-Link form stable thioether bonds with thiol-reactive groups on RGD-Dextran resulting in gel formation within 20 min. CD-Link is designed for MMP cleavage, allowing cell spreading/migration if they express the indicated MMPs. ToGro hydrogels can be dissolved by adding dextranase, allowing easy cell recovery. One kit allows formation of 2.4 ml ToGro Hydrogel. Manufactured in Germany by Cellendes GmbH.

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