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Cayman Chemical 3Deoxy3fluorothymIdIn 50mg
SDP

Supplier:  Cayman Chemical 3651950 MG

Encompass_Preferred

A nucleoside analog; a TK1 substrate; inhibits TK1 and TK2 (Kis = 6 and 10 µM, respectively); inhibits HIV-1 reverse transcriptase (EC50 = 5 nM) and the replication of HIV-1 in MT-4 cells (EC50 = 5 nM); decreases mtDNA levels and the OCR and induces upregulation of CD11b in OCI-AML-2 and MV4-11 cells; reduces tumor growth in an OCI-AML-2 AML mouse xenograft model at 50 mg/kg; a radiolabeled form is commonly used as a PET tracer for in vivo imaging of tumors

Catalog No. 50-291-2908


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