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Cayman Chemical 3MethylquInoxalIn2carboxy 50mg

Supplier: Cayman Chemical 2566450 MG

An antagonist of muscarinic acetylcholine receptors (Kis 5 14.5 3.7 5.3 and 40 nM for human recombinant M1-5 respectively) inhibits carbachol- induced intracellular calcium mobilization in bladder smooth muscle and submandibular gland cells isolated from cynomolgus monkeys (Kis 2 and 1 nM respectively) inhibits VIBC and OIS in rats (ID50s 0.062 and 0.089 mg/kg respectively) increases PD and LMA (ED50s 0.29 and 0.52 mg/kg respectively) and decreases SIT (ID50 0.22 mg/kg) in rats
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