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Medchemexpress LLC 3PO | 18550-98-6 | 99.9% | 210.23 | 5 MG
Supplier: Medchemexpress LLC HY198245MG
3PO is an inhibitor of PFKFB3 that attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. It suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH. This product is suitable for cancer research.
- Inhibits PFKFB3
- Attenuates proliferation of various cancer cell lines (IC50s of 1.4-24 μmol/L)
- Suppresses glucose uptake
- Decreases intracellular levels of Fru-2,6-BP, lactate, ATP, NAD+, and NADH
- Inhibits Jurkat cell proliferation by affecting the cell cycle
- Inhibits growth of Lewis lung carcinoma xenografts
- Inhibits tumor growth in MDA-MB231 human breast adenocarcinoma xenografts
- Inhibits tumor growth in HL-60 leukemia xenografts
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