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Medchemexpress LLC 3PO | 18550-98-6 | 99.9% | 210.23 | 50 MG
SDP

Catalog No. 5000401677
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3PO is an inhibitor of PFKFB3 that has been shown to attenuate the proliferation of several cancer cell lines with IC50s ranging from 1.4 to 24 μmol/L. It suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH. This product is intended for cancer research.

  • Inhibits Jurkat cells proliferation by influencing cell cycle.
  • Suppresses glycolytic flux to lactate in Jurkat cells.
  • Inhibits cellular proliferation of transformed tumor cell lines.
  • Suppresses the growth of Lewis lung carcinoma xenografts in C57Bl/6 mice.
  • Suppresses xenograft tumorigenic growth of MDA-MB231 cells.
  • Suppresses xenograft tumorigenic growth of HL-60 leukemia.
  • Decreases Fru-2,6-BP and glucose uptake in C57Bl/6 mice.

Catalog No. 50-004-01677 Supplier Medchemexpress LLC Supplier No. HY1982450MG
May include imposed supplier surcharges.
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3PO is an inhibitor of PFKFB3 that has been shown to attenuate the proliferation of several cancer cell lines with IC50s ranging from 1.4 to 24 μmol/L. It suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH. This product is intended for cancer research.

  • Inhibits Jurkat cells proliferation by influencing cell cycle.
  • Suppresses glycolytic flux to lactate in Jurkat cells.
  • Inhibits cellular proliferation of transformed tumor cell lines.
  • Suppresses the growth of Lewis lung carcinoma xenografts in C57Bl/6 mice.
  • Suppresses xenograft tumorigenic growth of MDA-MB231 cells.
  • Suppresses xenograft tumorigenic growth of HL-60 leukemia.
  • Decreases Fru-2,6-BP and glucose uptake in C57Bl/6 mice.

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