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Selleck Chemical LLC 3PO
Supplier: Selleck Chemical LLC S7639100MG
3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22 9 M for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity It suppresses glucose uptake and decreases the intracellular concentration of Fru-2 6-BP lactate ATP NAD and NADH
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