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Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 50mg, CAS: 13309-08-5; 18550-98-6.

Supplier: Apexbio Technology LLC B493950

3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
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