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Medchemexpress LLC 4-(2-aminoethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | 2341840-99-9 | MFCD32705128 | 99.4% | C15H16ClN3O5 | 10MG
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Supplier:  Medchemexpress LLC HY13616210MG

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Thalidomide-4-O-C2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in proteolysis-targeting chimera (PROTAC) research. It pairs a thalidomide-based CRBN-binding moiety with a short C2 aminoalkyl linker to enable conjugation to target ligands and recruitment of the E3 ubiquitin ligase for targeted protein degradation.

  • Designed to recruit cereblon E3 ligase in PROTAC constructs.
  • Short C2 aminoalkyl linker enables close proximity between ligand and E3 ligase.
  • Supplied as hydrochloride salt for improved stability and handling.
  • Characterized by analytical data, including H NMR and LC-MS.
  • High purity suitable for research applications.
  • Intended for research use only; not for human therapeutic use.

Catalog No. 50-002-60477


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