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Medchemexpress LLC 4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 871307-18-5 | MFCD10566771 | 99.4% | 404.83 g/mol | C21H14ClFN6 | 50MG
Supplier: Medchemexpress LLC HY1235850MG
Tpl2 Kinase Inhibitor 1 is a small-molecule, ATP-competitive inhibitor of the Tpl2 (MAP3K8/COT) kinase with demonstrated biochemical and cellular activity. It has a biochemical IC50 of 50 nM and reduces LPS-induced TNF-α production in cellular assays. The compound is supplied as a purified solid and is also available as a 10 mM solution in DMSO for research applications.
- Selective Tpl2 (MAP3K8) inhibitor with biochemical IC50 = 50 nM.
- Reduces LPS-induced TNF-α production in cellular assays (cellular IC50s reported).
- Molecular formula C21H14ClFN6; molecular weight 404.83 g/mol.
- Purity 99.42% as listed by supplier.
- Available as solid in multiple quantities and as 10 mM in 1 mL DMSO.
- Suitable for in vitro and cellular research applications.
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