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Medchemexpress LLC 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile | 871307-18-5 | 99.4% | 404.83 g/mol | C21H14ClFN6 | 100MG
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Supplier:  Medchemexpress LLC HY12358100MG

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Tpl2 Kinase Inhibitor 1 is a selective small-molecule inhibitor of Tpl2 (MAP3K8) used for biochemical and cell-based research. It demonstrates potent biochemical inhibition and documented cellular effects, and is supplied as a solid with defined purity and storage conditions for laboratory use.

  • Biochemical IC50 ≈ 50 nM for Tpl2 (MAP3K8).
  • Molecular weight 404.83 g/mol.
  • Chemical formula C21H14ClFN6.
  • Purity 99.4% (reported by manufacturer).
  • Appearance solid, yellow to green.
  • Available in solid sizes up to 100 mg.
  • Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
  • Documented cellular activity: <5 μM (A-431 cells) and 1.1 μM (monocytes).

Catalog No. 50-002-35975


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