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Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10144810MG

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TMI-1 is a small-molecule inhibitor of TNF-α converting enzyme (TACE/ADAM17) with activity against several ADAM and matrix metalloproteinase (MMP) family proteases. It has demonstrated antiproliferative and pro-apoptotic effects in cancer cell models and can suppress TNF-α secretion and inflammatory responses in preclinical studies. Supplied as a high-purity solid for research use.

  • Inhibits TACE (ADAM17) and multiple MMPs with low-nanomolar potency.
  • Demonstrates antiproliferative and apoptosis-inducing activity in cellular models.
  • Reduces TNF-α secretion and inflammatory markers in preclinical studies.
  • High purity solid suitable for biochemical and cellular assays.
  • Available in small mass packs for research applications.

Catalog No. 50-002-48189


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