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Medchemexpress LLC 4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one | 2172879-52-4 | >99.9% | 328.06 | 50 MG
Supplier: Medchemexpress LLC HY11270950MG
LIT-927 is a small molecule that acts as a neutraligand by binding to and neutralizing the chemokine CXCL12. Developed as an alternative strategy to inhibitors for CXCL12's cognate receptors CXCR4 or CXCR7, it functions as a potential anti-inflammatory agent.
- Locally and orally active
- Functions as a CXCL12 neutraligand
- Exhibits anti-inflammatory effects
- Binds to the specific receptor CXCR4 with a Ki of 267 nM for CXCL12 binding
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