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Medchemexpress LLC 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1-one | 1883429-21-7 | MFCD30489736 | >98.0% | 353.4 Da | C20H23N3O3 | 10 MM x 1 ML

Supplier: Medchemexpress LLC HY10035110MM 1ML
BI-7273 is a selective, cell-permeable bromodomain inhibitor primarily targeting BRD9 with secondary activity against BRD7. It has been characterized in biochemical, structural, and cellular assays and is supplied for research use in both concentrated DMSO solution and solid formats.
- High affinity for BRD9 (KD ≈ 15 nM) and low-nanomolar biochemical potency.
- Reduced activity against BRD7 (IC50 ≈ 117 nM), enabling differential target studies.
- High selectivity versus BET bromodomains (no measurable activity up to 100 μM).
- Supplied as a 10 mM solution in DMSO or as solid quantities for reconstitution.
- Typical purity ≥98% and molecular weight 353.4 Da.
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