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Sigma Aldrich 4-(4-(Prop-2-Yn-1-Yloxy)Benzoyl)Benzoic Acid

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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.Technology Spotlight: Trifuctional Probe Building BlocksA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSSynthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Specifications

CAS 2140866-80-2
Molecular Formula C17H12O4
Linear Formula C17H12O4
Quantity 10 g
Synonym 2,4,6-Trimercaptotriazine-functionalized silica gel; SiliaMetS(R) Dimercaptotriazine (DMT)
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