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Medchemexpress LLC 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-2 3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | 1137109-21-7 | 98.8% | 601.60 | 250 MG
Supplier: Medchemexpress LLC 250MGHYW008879
Mal-amido-PEG6-NHS ester is a PROTAC linker, based on PEG, that is utilized in the synthesis of PROTACs. PROTACs themselves are composed of two distinct ligands connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other to a target protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- PROTACs utilize the ubiquitin-proteasome system for selective protein degradation.
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