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Medchemexpress LLC 4,7,10,13-Tetraoxahexadec-15-ynoic acid | 1415800-32-6 | 97.0% | 5 G
Supplier: Medchemexpress LLC HY1304815G
Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs. It also serves as a click chemistry reagent, featuring an Alkyne group capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Supports synthesis of BTK-IAP PROTACs
- PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells
- Functions as a click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Appearance: Colorless to light yellow viscous liquid
- Molecular weight: 260.28
- Molecular formula: C12H20O6
- Solubility in DMSO: 50 mg/mL (192.10 mM)
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