Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000350201

Medchemexpress LLC 4,8-Methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-12-carboxylic acid, 7-(cyclopropylmethyl)-5,6,7,8,8a,9,14,14b-octahydro-1,8a-dihydroxy-, ethyl ester, (4bS,8R,8aS,14bR)- | 892039-23-5 | 99.44% | 486.56 | 100 MG
SDP

Catalog No. 5000350201
Encompass_Preferred

TAN-452 is an orally active, selective peripherally acting δ-opioid receptor (DOR) antagonist with a Ki of 0.47 nM and a Kb of 0.21 nM. It also acts as an antagonist for μ-opioid receptor (MOR; Ki=36.56 nM and Kb=9.43 nM) and κ-opioid receptor (KOR; Ki=5.31 nM and Kb=7.18 nM). TAN-452, a derivative of Naltrindole, exhibits low brain penetrability and can attenuate morphine-induced side effects without impacting pain control.

  • Orally active
  • Selective peripherally acting δ-opioid receptor (DOR) antagonist
  • Low brain penetrability
  • Attenuates morphine-induced side effects without affecting pain control
  • Antagonist for μ-opioid receptor (MOR) and κ-opioid receptor (KOR)

Catalog No. 50-003-50201 Supplier Medchemexpress LLC Supplier No. HY136208100MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

TAN-452 is an orally active, selective peripherally acting δ-opioid receptor (DOR) antagonist with a Ki of 0.47 nM and a Kb of 0.21 nM. It also acts as an antagonist for μ-opioid receptor (MOR; Ki=36.56 nM and Kb=9.43 nM) and κ-opioid receptor (KOR; Ki=5.31 nM and Kb=7.18 nM). TAN-452, a derivative of Naltrindole, exhibits low brain penetrability and can attenuate morphine-induced side effects without impacting pain control.

  • Orally active
  • Selective peripherally acting δ-opioid receptor (DOR) antagonist
  • Low brain penetrability
  • Attenuates morphine-induced side effects without affecting pain control
  • Antagonist for μ-opioid receptor (MOR) and κ-opioid receptor (KOR)

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.