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Cayman Chemical 4-AcetamIdo ntIpyrIn 25mg

Supplier: Cayman Chemical 4030825 MG

A TLR4 antagonist inhibits LPS-induced production of TNF-a and IL-6 in primary mouse macrophages (IC50s 0.89 and 0.53 UM respectively) inhibits LPS-induced TLR4-mediated NF-KB activation in a reporter assay using RAW 264.7 cells reduces lung macrophage infiltration and prevents lung edema and alveolar thickening in a mouse model of LPS-induced acute lung injury at 10 mg/kg
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