4-Acetylpyridine, 98%

Description

CAS: 1122-54-9 | C7H7NO | 121.139 g/mol

4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

Solubility
Insoluble in water. Soluble in alcohol.

Notes
Store in cool place. Keep away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1122-54-9
• Molecular Formula: C7H7NO
• Molecular Weight (g/mol): 121.139
• MDL Number: MFCD00006433
• InChI Key: WMQUKDQWMMOHSA-UHFFFAOYSA-N
• Synonym: 4-acetylpyridine, methyl 4-pyridyl ketone, ethanone, 1-4-pyridinyl, ketone, methyl 4-pyridyl, 1-pyridin-4-yl ethan-1-one, 1-pyridin-4-yl ethanone, pyridine, 4-acetyl, 4-acetyl pyridine, 4-pyridyl methyl ketone, unii-g47437iow7
• PubChem CID: 14282
• IUPAC Name: 1-pyridin-4-ylethanone
• SMILES: CC(=O)C1=CC=NC=C1

• Melting Point: 14°C to 16°C
• Density: 1.103
• Boiling Point: 210°C to 212°C
• Flash Point: 104°C (219°F)
• Refractive Index: 1.535
• Quantity: 25 g
• Beilstein: 107629
• Solubility Information: Insoluble in water. Soluble in alcohol.
• Formula Weight: 121.14
• Percent Purity: 98%
• Chemical Name or Material: 4-Acetylpyridine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	214-350-9
RTECSNumber	OB5426000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only