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Cayman Chemical 4-amIno NIcotInIc AcId 1g
SDP

Supplier:  Cayman Chemical 207331 G

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A p38a MAPK inhibitor (IC50 9 nM) selective for p38a over p38B MAPK (Ki 220 nM) as well as ERK JNK and a panel of 50 kinases at 2 UM inhibits LPS-induced production of IL-1B and TNF-a in isolated human PBMCs (IC50s 45 and 51 nM respectively) reduces disease severity in a type II collagen-induced mouse model of arthritis at 10 mg/kg

Catalog No. 50-298-4956


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