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Medchemexpress LLC 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | 327036-89-5 | MFCD04973552 | 99.8% | 222.26 g·mol⁻¹ | C10H10N2O2S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY110125MG

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TDZD-8 is a small-molecule, non-ATP-competitive inhibitor of glycogen synthase kinase-3β (GSK-3β) used in biochemical and cellular research to probe GSK-3β-regulated signaling pathways. It inhibits GSK-3β with an IC50 of approximately 2 μM and displays substantially weaker activity against several other kinases.

  • Selective inhibition of GSK-3β (IC50 ≈ 2 μM).
  • Reduced off-target activity against Cdk-1/cyclin B, CK-II, PKA, and PKC.
  • High purity suitable for biochemical and cellular assays.
  • Available in small-mass quantities and solution formats for assay convenience.
  • Molecular formula C10H10N2O2S; molar mass 222.26 g·mol⁻¹.

Catalog No. 50-002-64298


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