4-Cyclohexylaniline, 97%

Catalog No.	Quantity
AAL0318406	5 g
AAL0318403	1 g

Catalog No. AAL0318406 Supplier Thermo Scientific Chemicals Supplier No. L0318406

Description

CAS: 6373-50-8 | C16H12Cl2N4OS | 379.26 g/mol

4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.

Solubility
Insoluble in water.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6373-50-8
• Molecular Formula: C16H12Cl2N4OS
• Molecular Weight (g/mol): 379.26
• MDL Number: MFCD00001454
• InChI Key: YDTTUXLKBBQRHA-UHFFFAOYSA-N
• Synonym: benzenamine, 4-cyclohexyl, 4-cyclohexylbenzenamine, aniline, p-cyclohexyl, p-cyclohexylaniline, 4-cyclohexylphenyl amine, 4-cyclohexylphenylamine, 4-cyclohexylanilin, 4-cyclohexyl-aniline, acmc-20aivf, p-cyclohexylphenylamine
• PubChem CID: 80764
• IUPAC Name: 4-cyclohexylaniline
• SMILES: CC1=CC=C(C=C1)C1=NN=C(NC(=O)NC2=CC=C(Cl)C=C2Cl)S1

• Melting Point: 52°C to 56°C
• Boiling Point: 166°C (13 mmHg)
• Quantity: 5 g
• Beilstein: 2965799
• Solubility Information: Insoluble in water.
• Formula Weight: 175.28
• Percent Purity: 97%
• Chemical Name or Material: 4-Cyclohexylaniline

Safety and Handling

Hazard Category	H302+H312+H332-H315-H319-H335
Hazard Statement	GHS H Statement H302-H312 Harmful if swallowed. Harmful in contact with skin.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	228-918-9
TSCA	No

SDS

RUO – Research Use Only