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Cayman Chemical 4-DafachronIc AcId 10mg
Supplier: Cayman Chemical 1410010 MG
A racemic mixture of (25R)-Δ4-dafachronic acid and (25S)-Δ4-dafachronic acid; an agonist of DAF-12; a metabolite of cholesterol in C. elegans; induces transactivation of DAF-12 in NIH3T3 cells expressing the C. elegans or D. immitis receptor (EC50s = 81 and 0.65 nM, respectively); induces molting of infective D. immitis (heartworm) third-stage larvae into L4 larvae; induces the escape trajectory in embryos of the annual killifish A. limnaeus at 25°C at 75 µM
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