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4-(Dimethylamino)pyridine, 99%
Description
4-(Dimethylamino)pyridine is a useful nucleophilic catalyst for various reactions viz. esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation and Steglich rearrangement. It is also an effective catalyst for transesterification of beta-keto esters and silylation of alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
4-(Dimethylamino)pyridine is a useful nucleophilic catalyst for various reactions viz. esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation and Steglich rearrangement. It is also an effective catalyst for transesterification of beta-keto esters and silylation of alcohols.
Solubility
Soluble in methanol, benzene, ethyl acetate, chloroform, methylene chloride, acetone, and acetic acid. Slightly soluble in ether, diisopropyl ether, cyclohexane, hexane, and water.
Notes
Incompatible with strong oxidizing agents and strong acids.

Specifications
Specifications
Melting Point | 110°C to 113°C |
Boiling Point | 162°C (50 mmHg) |
Flash Point | 124°C (255°F) |
Assay Percent Range | 99% |
Quantity | 5 g |
UN Number | UN2928 |
Beilstein | 110354 |
Solubility Information | Soluble in methanol,benzene,ethyl acetate,chloroform,methylene chloride,acetone,and acetic acid. Slightly soluble in ether,diisopropyl ether,cyclohexane,hexane,and water. |
Formula Weight | 122.17 |
Percent Purity | 99% |
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Safety and Handling
Hazard Category | H301+H331-H310-H315-H318-H370 |
Hazard Statement | GHS H Statement H301-H310-H314-H318 Toxic if swallowed. Fatal in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage. |
Precautionary Statement | P260-P262-P264b-P270-P271-P280-P301+P310-P302+P350-P304+P340-P305+P351+P338-P307+P311-P310-P311-P330-P332+P313-P361-P363-P501c |
DOTInformation | Hazard Class: 6.1; Packaging Group: II |
EINECSNumber | 214-353-5 |
RTECSNumber | US9230000 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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