4-Fluoro-7-nitrobenzofurazan

Description

CAS: 29270-56-2 | C6H2FN3O3 | 183.098 g/mol

4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of functionalized hydroxynaphthofurazan, Spectrophotometric and spectrofluorometric determination of clemastine hydrogen fumarate, loratadine, losartan potassium and ramipril in pharmaceutical formulations. Synthesis of 7-nitrobenzofurazan (NBD)-labeled maleimide, via Diels-Alder reaction. NBD-Cl is widely used to label peptides, proteins, drugs and other biomolecules. It is also a popular derivatizing reagent for HPLC analysis

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of functionalized hydroxynaphthofurazan, Spectrophoto

Specifications

Chemical Identifiers

• CAS: 29270-56-2
• Molecular Formula: C6H2FN3O3
• Molecular Weight (g/mol): 183.098
• MDL Number: MFCD00010196
• InChI Key: PGZIDERTDJHJFY-UHFFFAOYSA-N
• Synonym: 4-fluoro-7-nitrobenzofurazan, nbd-f, 4-fluoro-7-nitrobenzo c 1,2,5 oxadiazole, 7-fluoro-4-nitrobenzofurazan, 7-fluoro-4-nitrobenzo-2-oxa-1,3-diazole, 4-fluoro-7-nitrobenz-2-oxa-1,3-diazole, 2,1,3-benzoxadiazole, 4-fluoro-7-nitro, nbd-fluoride, nbd-f cpd, 4-fluoro-7-nitrobenzo c 1,2,5-oxadiazole
• PubChem CID: 122123
• IUPAC Name: 4-fluoro-7-nitro-2,1,3-benzoxadiazole
• SMILES: C1=C(C2=NON=C2C(=C1)F)[N+](=O)[O-]

• Melting Point: 53°C to 57°C
• Color: Yellow
• Flash Point: 110°C (230°F)
• Quantity: 100 mg
• Beilstein: 1077571
• Solubility Information: It is soluble in DMSO,DMF,CH3OH,CH3CN and CHCl3.
• Formula Weight: 183.1
• Physical Form: Powder
• Chemical Name or Material: 4-Fluoro-7-nitrobenzofurazan

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only