4-Hydroxy-1-methylpiperidine, 98%

Description

CAS: 106-52-5 | C6H13NO | 115.176 g/mol

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

Solubility
Soluble in water.

Notes
Hygroscopic. Store under dry inert gas. Store away from moisture and oxidizing agents. Incompatible with water and oxidizing agents. Store at 4°C.

Specifications

Chemical Identifiers

• CAS: 106-52-5
• Molecular Formula: C6H13NO
• Molecular Weight (g/mol): 115.176
• MDL Number: MFCD00006500
• InChI Key: BAUWRHPMUVYFOD-UHFFFAOYSA-N
• Synonym: 4-hydroxy-1-methylpiperidine, n-methyl-4-piperidinol, 1-methyl-4-piperidinol, 4-hydroxy-n-methylpiperidine, n-methyl-4-hydroxypiperidine, 4-piperidinol, 1-methyl, 1-methyl-4-hydroxypiperidine, n-methylpiperidol, n-methyl-4-hydroxy piperidine, 4-hydroxy-1-methyl-piperidine
• PubChem CID: 66048
• IUPAC Name: 1-methylpiperidin-4-ol
• SMILES: CN1CCC(CC1)O

• Melting Point: 26°C to 30°C
• Density: 0.98
• Boiling Point: 198°C to 200°C
• Flash Point: 87°C (188°F)
• Refractive Index: 1.479
• Quantity: 500 g
• Beilstein: 103024
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water.
• Formula Weight: 115.18
• Percent Purity: 98%
• Chemical Name or Material: 4-Hydroxy-1-methylpiperidine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	203-406-8
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only