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Medchemexpress LLC 4-Hydroxybenzylidenemalononitrile | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 25 MG
Supplier: Medchemexpress LLC HYW17427925MG
Tyrphostin 8 (4-hydroxybenzylidenemalononitrile, CAS 3785-90-8) is a small-molecule tyrosine kinase inhibitor reported to target EGFR, with additional activity against GTPases and the serine/threonine phosphatase calcineurin. Provided for research use in solid and DMSO solution formats, it has molecular formula C10H6N2O, molecular weight 170.17 g/mol, and listed purity 98.0%.
- Reported EGFR inhibitor (IC50 = 560 μM).
- Inhibits calcineurin phosphatase activity (IC50 = 21 μM).
- Also reported to inhibit GTPase activity.
- Supplied as solid and as 10 mM solution in DMSO for assay flexibility.
- Listed purity 98.0% suitable for biochemical research.
- Chemical formula C10H6N2O; molecular weight 170.17 g/mol.
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