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Sigma Aldrich (4-Hydroxyphenyl)(4-(Prop-2-Yn-1-Yloxy)Phenyl)Methanone

Catalog No. 900615100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-061-5100MG 50 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.Technology Spotlight: Trifuctional Probe Building BlocksA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSDesign, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoidsClickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulatorsgamma-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin

Specifications

CAS 2140866-79-9
Molecular Formula C21H20O5
Linear Formula C21H20O5
Quantity 50 mg
Synonym Carboxyl benzophenone alkyne; Probe building block
Molecular Weight (g/mol) 352.38 g/mol
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