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Cayman Chemical 4-HydroxyphenylpyruvIc AcId 1g
Supplier: Cayman Chemical 385081 G
An intermediate in aromatic amino acid metabolism; inhibits LPS-induced IL-6 and NO production in RAW 264.7 macrophages (IC50s = 2 and 0.5 mM, respectively); decreases serum starvation-induced mitochondrial superoxide production in EA.hy926 endothelial cells in vitro; increases survival in a rat model of hemorrhagic shock; serum and urinary levels are increased in patients with alkaptonuria
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