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Cayman Chemical 4-HydroxyquInolIn 1g
SDP

Supplier:  Cayman Chemical 350641 G

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A GABAA binds to rat synaptic cortical membranes (Ki 55 nM) activates a1B2Y2S a2B2Y2S a3B2Y2S a5B2Y2S and 1 subunit-contanining GABAA receptors in a FLIPR assay (EC50s 13 4 5 5 6 0 78 and 3 1 UM respectively) inhibits CA1 population spikes in rat hippocampal slices (EC50 13 UM) inhibits potassium/low magnesium-induced seizures in rat pups chronic administration improves tactile over-reactivity anxiety-like behaviors and social impairments in mouse models of ASD at 2 mg/kg

Catalog No. 50-291-0479


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