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Cayman Chemical 4-MethoxyphenylD-Glucopyra 5g

Supplier: Cayman Chemical 358185 G
A Chk1 inhibitor (IC50 1 2 nM) 30-fold selective for Chk1 over a panel of more than 450 wild-type and mutant kinases enhances cytarabine-induced apoptosis in HL-60 KG-1 U937 and ML-1 AML cells nearly completely eliminates tumor burden in AML PDX mouse models at 7 5 mg/kg in combination with cytarabine
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