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Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | >99.9% | 338.31 | 50 MG
Supplier: Medchemexpress LLC HY13787350MG
4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase. It releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage, which exhibits pH-dependent fluorescence excitation. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Fluorescent substrate for alpha-glucosidase
- Releases 4-methylumbelliferyl (4-MU) upon cleavage
- 4-MU has pH-dependent fluorescence excitation activity
- Excitation wavelengths are 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3)
- Emission wavelength increases with decreasing pH, ranging from 445-455 nm
- Useful as a biomarker for Fabry and Pompe diseases
- Quantifies alpha-glucosidase activity in infant blood spot samples
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