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Medchemexpress LLC 4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimidine-4,6-dicarboxamide | 544678-85-5 | MFCD09878513 | 99.2% | 410.42 g/mol | C22H20F2N4O2 | 5MG
SDP

Supplier:  Medchemexpress LLC HY1251665MG

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DB04760 is a potent, highly selective, non-zinc-chelating inhibitor of matrix metalloproteinase-13 (MMP-13) with a reported IC50 of 8 nM. In preclinical studies it reduced paclitaxel-induced neurotoxicity and exhibited anticancer activity. The compound is supplied for research use in multiple solid and solution formats and is provided with high purity.

  • Potent MMP-13 inhibitor (IC50 = 8 nM).
  • Non-zinc-chelating mechanism reduces off-target zinc interaction risk.
  • Shown to reduce paclitaxel-induced neurotoxicity in studies.
  • Exhibits anticancer activity in reported preclinical work.
  • High purity (≈99.2%) with molecular weight 410.42 and formula C22H20F2N4O2.
  • Available in solid and DMSO solution formats for research applications.

Catalog No. 50-002-38677


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