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Medchemexpress LLC 4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopentan[c]quinoline-8-sulfonamide | 353483-92-8 | MFCD01080566 | >98.0% | 376.47 g/mol | C22H20N2O2S | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10768210MG

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TQS is a type II positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR) used in preclinical research to potentiate agonist-evoked responses and reduce receptor desensitization. It is employed in studies of neuroinflammation and pain; chemically it is C22H20N2O2S with a molecular weight of 376.47 g/mol.

  • Enhances α7 receptor currents and reduces desensitization.
  • Type II positive allosteric modulation with pEC50 ≈ 5.5.
  • High reported purity (≥98% by HPLC).
  • Soluble in DMSO for solution preparations.
  • Supplied as solid or as DMSO solution for laboratory use.

Catalog No. 50-002-40019


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