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Medchemexpress LLC (4-NH2)-Exatecan | 2495742-21-5 | 99.9% | C23H21N3O4 | 1 ML
SDP

Catalog No. 5000356002
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(4-NH2)-Exatecan is a topoisomerase inhibitor and a derivative of Exatecan. It is used in the synthesis of antibody-drug conjugates (ADCs). This compound contains a linker for connecting to a Ligand Unit, where the linker is cleavably attached to the amino residue, characterized by the addition of an amino (NH2) functional group at the 4th position of the parent molecule.

  • Inhibits topoisomerase
  • Used in synthesis of antibody-drug conjugates (ADCs)
  • Exhibits in vitro antitumor activity against P388 (murine leukemia) cells (IC50 2.97 ng/mL)
  • Exhibits in vitro antitumor activity against QG-56 (human lung cancer) cells (IC50 1.38 ng/mL)
  • Relevant to cancer research and drug development, including targeted therapy and immunotherapy

Catalog No. 50-003-56002 Supplier Medchemexpress LLC Supplier No. HY14539710MM/1ML
May include imposed supplier surcharges.
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(4-NH2)-Exatecan is a topoisomerase inhibitor and a derivative of Exatecan. It is used in the synthesis of antibody-drug conjugates (ADCs). This compound contains a linker for connecting to a Ligand Unit, where the linker is cleavably attached to the amino residue, characterized by the addition of an amino (NH2) functional group at the 4th position of the parent molecule.

  • Inhibits topoisomerase
  • Used in synthesis of antibody-drug conjugates (ADCs)
  • Exhibits in vitro antitumor activity against P388 (murine leukemia) cells (IC50 2.97 ng/mL)
  • Exhibits in vitro antitumor activity against QG-56 (human lung cancer) cells (IC50 1.38 ng/mL)
  • Relevant to cancer research and drug development, including targeted therapy and immunotherapy

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