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Cayman Chemical 4-oxo IsotretInoIn 10mg
Supplier: Cayman Chemical 3438810 MG
An active metabolite of isotretinoin; increases protein expression of CK7 and CK19 in normal human epidermal keratinocytes at 10 µM; inhibits proliferation of retinoid-sensitive UM-SCC-22A and UM-SCC-35 HNSCC cells; has been found in influent and effluent wastewater; is teratogenic to embryos when administered to pregnant dams at 100 mg/kg on day 11 of gestation
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