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Cayman Chemical 4-oxo Retinoic Acid, Purity: ≥95%, CAS: 38030-57-8, 5 mg
SDP

Catalog No. 502911108
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An active metabolite of all-trans retinoic acid; binds to RARα, RARβ, and RARγ (IC50s = 59, 50, and 142 nM, respectively, in radioligand binding assays) and induces expression of a luciferase reporter in COS-7 cells expressing RARα, RARβ, or RARγ (EC50s = 33, 8, and 89 nM, respectively); increases protein levels of CK-7 and CK-19 in human epidermal keratinocytes at 1 µM; inhibits the proliferation of MCF-7 breast cancer cells at 10-1,000 nM; is teratogenic to zebrafish embryos (EC50 = 8.1 nM)

Catalog No. 50-291-1108 Supplier Cayman Chemical Supplier No. 358195 MG
May include imposed supplier surcharges.
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An active metabolite of all-trans retinoic acid; binds to RARα, RARβ, and RARγ (IC50s = 59, 50, and 142 nM, respectively, in radioligand binding assays) and induces expression of a luciferase reporter in COS-7 cells expressing RARα, RARβ, or RARγ (EC50s = 33, 8, and 89 nM, respectively); increases protein levels of CK-7 and CK-19 in human epidermal keratinocytes at 1 µM; inhibits the proliferation of MCF-7 breast cancer cells at 10-1,000 nM; is teratogenic to zebrafish embryos (EC50 = 8.1 nM)

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